| abstract |
The present invention provides a chemically stable type 1 placental growth factor (PLGF-1), a method of preparation thereof, a therapeutic and cosmetic use thereof, and a derivative thereof, wherein the cysteine residue is substituted or removed from the amino acid sequence of a naturally occurring protein. It relates to pharmaceutical and cosmetic compositions. The present invention also relates to methods of making antibodies to such inducers and to their use in the diagnosis and treatment of tumors and non-tumoral lesions. |