http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20040111051-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7aa3dcd59d6312b06890df3363d124dc |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-027 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2004-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4347e572a86d4a1490bd7f0de235edf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7bae0b238b6f5202c4ee38047320879 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4065c0522b0a51d0d87f1cef332e6a75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31ae802c9f2c81aee86a46549d2e80db |
| publicationDate | 2004-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20040111051-A |
| titleOfInvention | Composition for screening anti-hypertension drug comprising mammal TCTP gene or its protein product, and method for screening anti-hypertension drug using said composition |
| abstract | The present invention relates to an antihypertensive screening composition comprising a mammalian TCTP gene or a protein expressed therefrom and an antihypertensive screening method using the same.n n n TCTP included in the composition of the present invention acts as a cytoplasmic inhibitor of the sodium / potassium APTase pump, causing hypertension and cardiac hypertrophy.n n n Therefore, the composition of the present invention and the screening method using the same can be usefully used for the search and development of antihypertensive agents.n n n In addition, the transgenic mice overexpressing the TCTP of the present invention exhibits hypertension and cardiac hypertrophy as a phenotype, and by administering a test substance developed for the treatment and improvement of hypertension or cardiac hypertrophy, by examining the degree of treatment and improvement, It can be usefully used for screening the target material. |
| priorityDate | 2003-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 452.