http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20040096661-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 |
| filingDate | 2003-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2004-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20040096661-A |
| titleOfInvention | Heterocyclic amide derivatives as inhibitors of glycogen phosphorylase |
| abstract | The present invention provides a heterocyclic amide or a pharmaceutically acceptable salt or prodrug thereof of Formula 1, which has glycogen phosphorylase inhibitory activity and is useful for the treatment of disease states associated with increased glycogen phosphorylase activity. to provide.n n n Formula 1n n n n n n n n In the above formula,n n n X is N or CH;n n n R 4 and R 5 together are —SC (R 6 ) = C (R 7 ) — or —C (R 7 ) = C (R 6 ) -S—;n n n R 6 and R 7 are independently selected from, for example, hydrogen, halo and C 1-4 alkyl;n n n A is phenylene or heteroarylene;n n n n is 0, 1 or 2;n n n R 1 is independently selected from halo, nitro, cyano, hydroxy, carboxy;n n n R 2 is hydrogen, hydroxy or carboxy;n n n R 3 is for example hydrogen, hydroxy, aryl, heterocyclyl and C 1-4 alkyl optionally substituted with one or two R 8 groups;n n n R 8 is, for example, hydroxy, -COCOOR 9 , -C (O) N (R 9 ) (R 10 ), -NHC (O) R 9 , -NHSO 2 R 9 , (R 9 ) (R 10 ) N- and -COOR 9 ;n n n R 9 and R 10 are, for example, selected from hydrogen, hydroxy, C 1-4 alkyl optionally substituted with one or two R 13 ;n n n R 13 is selected from hydroxy, halo, trihalomethyl and C 1-4 alkoxy.n n n The present invention is also described with respect to the preparation of such heterocyclic amide derivatives and pharmaceutical compositions containing them. |
| priorityDate | 2002-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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