| abstract |
An object of the present invention is to search for an additive that enhances the antiseptic effect of a cationic preservative in the case of blending a cationic preservative into an eye drop containing a compound having a chemical structure of the general formula (I). When the basic amine compound is blended into an eye drop containing a compound having the chemical structure of formula (I) and a cationic preservative, the antiseptic effect of the eye drop is remarkably enhanced. In formula (I), R 1 represents a group having a compound represented by the following structural formulas (Ia), (Ib), (Ic), (Id), (Ie) or (If).n n n n Formula I |