abstract |
summary :n n n A process for preparing 3-O-substituted 5,6-hydroxy group protected L-ascorbic acid, used as intermediate for the preparation of 3-O-substituted L-ascorbic acid,n n n 5,6-hydroxy protected L-ascorbic acid is reacted with a compound which provides a protecting group protecting the hydroxyl groups at positions 5 and 6 of L ascorbic acid and L ascorbic acid in the presence of an acid catalyst and a solvent. To prepare a base continuously without a separate separation step, and reacted with RX (any compound selected from alkyl halides, alkenyl halides, R has 1 to 5 carbon atoms) to 5-O-substituted 5, Process for preparing 6-hydroxy group protected L-ascorbic acid in one step |