| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cbffa3b81b3b862dc7220b5648f5f745 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-5434
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
| filingDate |
2003-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bcf6d076bb87637791ba81165e61cdfc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f0b89db623c4fc90b19a7b39bfb44d9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68bb17b9927e7483bf89726e44b89c72 |
| publicationDate |
2004-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20040081237-A |
| titleOfInvention |
Method for producing target proteins by deleting or amplifying ibpA and/or ibpB gene coding for inclusion body-associated proteins |
| abstract |
The present invention relates to a method for preparing a protein of interest by lacking or amplifying genes ( ibpA and / or ibpB ) encoding inclusion body-associated proteins. The present invention provides two methods for preparing a target protein using genes ( ibpA and / or ibpB ) encoding an inclusion body binding protein derived from E. coli, which has not been reported to affect the production of the target protein. First, to provide a method for improving the secretory production and activity of the protein of interest using bacteria lacking ibpA and / or ibpB . Secondly, the present invention relates to a method of increasing productivity of target proteins produced in the cytoplasm using ibpA and / or ibpB amplified bacteria, as well as producing a target protein as an insoluble inclusion body in a water-soluble form, thereby providing many advantages to bioprocessing. |
| priorityDate |
2003-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |