| abstract |
The present invention is a compound of formula 1 that inhibits the activity of cholesterol acyl transferase (Acyl-CoA: Cholesterol Acyltransferase (ACAT)) and farnesyl protein transferase (FPT) isolated from lxeris dentata forma albiflora Sesquiterpene lactone compound (sesquiterpene lactone) compound and a composition comprising the same, the sesquiterpene lactone compound of Formula 1 is a cardiovascular disease and pancreatic cancer, such as arteriosclerosis, hypertension, angina pectoris, hyperlipidemia, myocardial infarction or heart failure, It can be usefully used for the prevention and treatment of cancers, such as bladder cancer, lung cancer and skin cancer.n n n <Formula 1> |