| abstract |
The present invention relates to addition salts with a compound of formula (I), an isomer thereof, or a pharmaceutically acceptable acid or base:n n n n n n n n Wheren n n R 1 is a hydroxy group or a RCO-O- group,n n n R 2 is hydrogen, a halogen atom, a hydroxy group or a R'CO-O- group,n n n R and R 'are the same or different and are substituted or unsubstituted alkyl groups,n n n R 3 is a hydrogen atom, an alkyl group or a cycloalkyl group,n n n A is CR 4 R 5 or NR 4 n n n R 4 is a hydrogen atom or an alkyl group.n n n The compounds are used for the treatment or prevention of memory and learning disorders associated with aging, anxiety or depressive syndrome, progressive neurodegenerative diseases, Alzheimer's disease, Peak disease, Huntington's chorea, schizophrenia, sequelae of acute neurodegenerative diseases, ischemic sequelae and epileptic sequelae. It is useful as an AMPA modulator for the treatment. |