| abstract |
The present invention relates to a bioerodible, biocompatible polymer, a solvent which is an aromatic alcohol having a water miscibility of 7% or less at 25 ° C. in an amount effective to plasticize the polymer and form a gel therewith, A catheter injectable depot composition is provided comprising a denatured composition and a beneficial agent. The solvent includes aromatic alcohols, esters of aromatic acids, aromatic ketones or mixtures thereof. The composition has substantially improved shear thinnig behavior and low injection force and is easily inserted below the body surface of the patient. |