http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20040050438-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_87853b5a2c2a56c6c14b7c380dd9cad4 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-56 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-56 |
| filingDate | 2002-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_385d3df0a642ee3cbd4bf12549aed0a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e53b605479a278f2c43e215787d5aaa1 |
| publicationDate | 2004-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20040050438-A |
| titleOfInvention | Novel process for preparing cefditoren |
| abstract | The present invention relates to ceftitorene coating chambers, namely 7- [2-methoxyimino-2- (2-aminothiazol-4-yl) acetamido] -3- [2- (4-methylthiazole-5 -Yl) vinyl] -3-cepem-4-carboxylic acid pivaloyloxymethyl ester compound, wherein the starting material of formula (II) is reacted with an organic solvent and a catalyst of formula (III) A first step of reacting a metal alkene compound such as 2-bis-tributylstannanyl ethene to obtain an intermediate compound of the following structural formula (IV) of the Z type, and a reaction agent of the intermediate compound with the cefem compound of the general formula (V). By carrying out the two-step process continuously to prepare the ceftitorene coating compound of the general formula (I), it is possible to simplify the existing process, to replace the conventionally known low yield non-economic preparation It is possible to provide a method for producing ceftitorene coating chamber of high purity and high yield.n n n (Ⅰ)n n n (Ⅱ)n n n (Ⅲ)n n n (Ⅳ)n n n (Ⅴ)n n n In the above formula,n n n R 1 is an alkyl group having 1 to 5 carbon atoms,n n n X is a halogen atom, chlorine, bromine, iodine atom,n n n Y is a halogen atom, triflate (-OTf), mesylate (-OMs) or tosylate (-OTs) group, and PMB is a paramethoxybenzyl group which is a carbonyl protecting group. |
| priorityDate | 2002-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 151.