abstract |
Prodrugs of compounds represented by formula (I), salts of these compounds, or any of these:n n n n n n n n [Wherein Ar represents an optionally substituted cyclic group; X represents a spacer with a bond or C 1-6 backbone; R 1 and R 2 are the same or different and each represents a hydrogen atom or an optionally substituted hydrocarbon group, or R 1 and R 2 can form an optionally substituted nitrogen-containing heterocycle with an adjacent nitrogen atom; Y represents an optionally substituted divalent hydrocarbon group (except CO); R 3 represents a hydrogen atom or an optionally substituted hydrocarbon group; Ring A and Ring B may each have different substituent (s), and if Ring B has another substituent, said substituents may be bonded to R 1 to form a ring.n n n They have an antagonistic action on melamine-concentrating hormones and are therefore useful as antiobesity / treatment agents and the like. |