http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20040045238-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_143ac4fbe1e063c6a828a96cfffc34d5 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1676 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 |
| filingDate | 2002-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_384b98d4fe10424f0b843020dd8bb770 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adfa8f3bd230dd2b9ca6108c2a993c0e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3bc8632ee3bacd37fec3b28489ba1b12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_599d8e8887cc618e847c159c7e7c330e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_493d5af4827d2772631ea54969e2b288 |
| publicationDate | 2004-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20040045238-A |
| titleOfInvention | Pellet preparations and methods for improved solubility of itraconazole |
| abstract | The present invention relates to solubilized itraconazole pellets and a method for preparing the same, specifically, 1-50 parts by weight of itraconazole, 0.1-40 parts by weight of surfactant, 0.5-30 parts by weight of water-soluble polymer are mixed with a solvent to dissolve or disperse itraconazole, As a pharmaceutically acceptable additive, 0.1-20 parts by weight of an organic acid or an inorganic acid including succinic acid is dissolved and mixed, followed by spray drying, spray drying the spray dried on inert spherical particles having a size of 100-1500 μm and pellets of a constant size. Alternatively, the spray dried material is mixed with 0-30 parts by weight of an oil or a fatty acid thereof to prepare a milky white emulsion, and a pellet having a size of 100-1500 μm prepared by spraying the reaction solution using a dispersing apparatus and a method of preparing the same As a result, it is an efficient method for improving the stability, solubility and handleability of itraconazole. |
| priorityDate | 2002-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 152.