| abstract |
The present invention uses DNA transduction domain (PTD) and DNA / RNA binding factor to bind eukaryotic DNA / RNA that encodes a substance that modulates biological function in vivo and in vitro . Or to a method for effective delivery into the cytoplasm or nucleus inside the prokaryotic cells, especially in vivo through the various routes including intramuscular, intraperitoneal, intravenous, oral, nasal, subcutaneous, intradermal, mucosal and inhalation I can deliver it. Therefore, the present invention is used in the technology of expressing transiently or permanently by delivering DNA / RNA to various cells and cells in medical applications and basic research fields such as DNA / RNA vaccine (vaccine) and gene therapy. Can be. |