abstract |
The present invention relates to an amino acid sequence of a synthetic E2 protein comprising a consensus sequence which is the most conserved amino acid found in E2 of 77 different HCV 1b isolates from around the world, and thus a nucleic acid sequence. It is about. The invention also relates to a truncated version of the E2 protein lacking HVR1. The present invention also relates to a vaccine comprising the E2 protein. |