| abstract |
The present invention relates to an anticonvulsant substance isolated from the extract of Lettuce (Lactuca savita). More specifically, seizures, convulsions, epilepsy, etc. are caused by the deficiency of γ-aminobutyrate (GABA), a neurotransmitter. It can be treated by increasing the amount of GABA by inhibiting the activity of the enzyme γ-aminobutyrate transaminase (GABA transaminase; GABA-T) and succinic semialdehyde dehydrogenase (SSADH). Therefore, the present invention is to provide a separate substance that is effective in the above diseases from the lettuce extract. |