abstract |
The present invention provides nucleic acid molecules comprising all or part of a daptomycin biosynthetic gene. The daptomycin biosynthetic gene cluster is streptomyces, preferably S. aureus. It may be derived from Roseosporus. The present invention is also referred to as S. Provided are other nucleic acid molecules from Roseosporus. The present invention further provides a polypeptide encoded by the nucleic acid molecules, an antibody specifically binding to the polypeptide, and a method for producing daptomycin and other compounds using the nucleic acid molecule, polypeptide and antibody. |