abstract |
The present invention relates to compounds of formula (I), isomers thereof, hydrates thereof, solvates thereof and addition salts thereof with pharmaceutically acceptable acids:n n n n n n n n In the above formula,n n n V is a single bond or an alkylene chain,n n n M is a single bond or an alkylene chain,n n n A and E are each a nitrogen atom or a CH group, at least one of these A or E is a nitrogen atom,n n n W is a group of formula (i), (ii) or (iii):n n n n n n n n Wherein X is a carbonyl, sulfonyl or sulfoxide group,n n n G 1 , G 2 and G 3 are as defined in the detailed description,n n n T is a fused phenyl group or a fused pyridyl group,n n n R 1 is a hydrogen atom, a linear or branched (C 1 -C 6) alkyl group, an aryl group or an alkyl moiety bilinear or branched aryl - and (C 1 -C 6) alkyl group,n n n R 2a and R 2b are the same or different and as defined in the detailed description,n n n R 3 is aryl or a hetero-A group as defined in the description, each of which may be substituted or unsubstituted,n n n Y is aryloxy, heteroaryloxy or a heteroaryl-B group as defined in the description, each of which may or may not be substituted). |