| abstract |
The present invention relates to an excellent chronic arthritis rheumatoid therapeutic agent comprising an aminostibazole derivative represented by the following formula (1) or a salt thereof as an active ingredient.n n n Formula 1n n n A-B-D-En n n Wherein A is heteroaryl or oxide thereof, B is ethenylene, D is phenylene, E is formula -N (R) SO 2 -G, where G is phenyl, and R is hydrogen, alkyl , -COR 0 and the like, wherein R 0 represents alkyl, alkoxy, aryloxy, 5- to 6-membered heteroaryl, heteroarylmethyl, aminoalkylene or cyclic aminoalkylene. |