| abstract |
The present invention provides compounds of formula I in free or salt form.n n n n n n n n Wherein Ar is a monovalent aromatic group of C 6 -C 15 , R 1 is hydrogen, halogen, cyano, hydroxy, C 1 -C 8 -alkyl, C 1 -C 8 -haloalkyl, C 1 -C Phenyl optionally substituted with one or more substituents selected from 8 -alkoxy, C 1 -C 8 -alkoxy-C 1 -C 8 -alkyl or acyloxy, or a 5- or 6-membered monovalent heterocyclic group, R 2 is hydrogen, C 1 -C 8 -alkyl, acyl or -CON (R 3 ) R 4 , provided that when R 1 is hydrogen, R 2 is C 1 -C 8 -alkyl, acyl or -CON (R 3 R 4 , R 3 and R 4 each independently represent a hydrogen or C 1 -C 8 -alkyl, or a 5- or 6-membered heterocyclic group together with the nitrogen atom to which they are attached, Z 1 , Z 2 , Z 3 and Z 4 are each independently N or CR 5 , at least one of them is CR 5 , and R 5 is hydrogen, C 1 -C 8 -alkyl or C 1 -C 8 -alkoxy. |