| abstract |
The present invention relates to a pharmaceutical composition comprising a compound of formula (1) capable of inhibiting the activity of protein tyrosine phosphatase 1B (PTP1B), the pharmaceutical composition of the present invention effectively inhibits the activity of PTP1B PTP1B inhibitor Or as a pharmaceutical composition for the treatment or prevention of obesity or diabetes.n n n n n n n n n n Wheren n n R is an aromatic group or a nitrogen, sulfur or oxygen-containing heterocyclic aromatic group, substituted or unsubstituted with halogen, alkyloxy, alkyl, amino, alkyl amino, carboxylic acid or amide. |