http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20030091952-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-472 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate | 2001-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2003-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20030091952-A |
| titleOfInvention | Specific human antibodies for selective cancer therapy |
| abstract | The present invention relates to peptides or polypeptides comprising Fv molecules, constructs thereof, fragments or constructs of any of these having enhanced binding properties to selectively and / or specifically bind to target cells for other cells. Wherein the binding selectivity or specificity is primarily determined by the first hypervariable portion, where Fv is scFv or dsFv and optionally has one or more tags. Improved binding relates to a binding site that is substantially exposed and / or overexpressed on or in a target comprising cells for other cells on or within which the binding site is substantially unavailable and / or not expressed. will be. The invention also relates to a method for isolating said peptides and polypeptides obtained from phage display libraries and nucleic acid molecules encoding them. The present invention provides pharmaceutical compositions and kits for the diagnosis and treatment of diseases, in particular cancer, more particularly acute myeloid leukemia, comprising the peptides or polypeptides. |
| priorityDate | 2000-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 483.