Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_af60af551d0a9b35a8111bb436232d36 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55511 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-01 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-09 |
filingDate |
2002-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95fe4d0d7e6fe397002fef8685001c1e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2b7eba984da9b27068731d67107e85d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d656e4a8ae2b35f90fa52ddffcafe956 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7d6966dfd1340aab74e8440cd92bf10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f271cc67dfda5d971a2f8fe288af2efe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1f10db544c4c2d96de1325642ab6c5d |
publicationDate |
2003-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20030091247-A |
titleOfInvention |
Non-oral vaccine for preventing dental caries using mannose-coated polymeric micelle-immunoregulator-immunogen complex |
abstract |
The present invention relates to a parenteral vaccine for immunologically preventing dental caries, and the parenteral vaccine for immunologically preventing dental caries is a disadvantage of the conventional oral vaccine, that is, a large amount is required and orally administered. It can be destroyed by post-digestive enzymes and has an excellent effect on compensating for disadvantages such as causing an immunological reaction. In addition, the present invention is an immunomodulatory agent for macrophage specific nanoparticles (mannose-coated polymeric micelle) having uniform particle size, large surface area, and easy to disperse or separate in water. It carries retinoic acid and selectively delivers to target organs or cells to reduce side effects of drugs, induces the production of high-efficiency antigen-specific immunoglobulins (IgA), and increases the antigen-specific IgA producing lymphocytes in the blood. Excellent effect. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108697141-A |
priorityDate |
2002-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |