http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20030090918-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_319ac9d729dcf44fc0463b2d37d25e6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fa0a8a718cac5315e779c640ffd410b4 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10032 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-761 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 |
| filingDate | 2002-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13731a8ccab009be72d04032062b30d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bced27a1d93849ea247d70643d08df63 |
| publicationDate | 2003-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20030090918-A |
| titleOfInvention | Recombinant Adenovirus with Enhanced Tumoricidal Effect and Pharmaceutical Composition Comprising the Same |
| abstract | The present invention relates to recombinant adenoviruses having an improved tumor killing effect. The present invention provides a recombinant adenovirus and a pharmaceutical antitumor composition comprising the same by introducing an infective ligand of a vesicular stomatitis virus into an adenovirus to enhance antitumor activity. The recombinant adenovirus of the present invention enables high efficiency gene delivery with the administration of a smaller amount of virus, thereby overcoming disadvantages such as inducing the immune response of the host and inducing toxicity, which are the biggest limitations of the gene delivery system using adenovirus. Therefore, it may be widely used in tumor cells with low gene transduction rate and cells with severe toxicity and side effects caused by administration of high titer of adenovirus. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017155281-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10849987-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019066535-A1 |
| priorityDate | 2002-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.