| abstract |
The present invention relates to a flavanone ester derivative of the general formula (1) and a pharmaceutical composition comprising the same, the compounds of the present invention have little toxicity, excellent blood lipid lowering effect, cholesterol metabolism-related enzyme inhibitory effect, atherosclerosis prevention and treatment Indicates.n n n n n n n n n n Wheren n n R 1 is a R 5 CO- group;n n n R 2 is H or a R 5 CO- group;n n n R 3 is H, CH 3 , R 5 CO- or R 6 group;n n n R 4 is H, OH, R 5 COO- or OR 6 group;n n n R 5 is a C 1 -C 18 alkyl group;n n n R 6 is a C 2 -C 18 alkyl or alkenyl group. |