| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_29cb876ab3c9bd2342db3855921c4464
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a9088561926a72d4bf7f9fc4fe133884
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a0ea792507eb2007fbb3b887480743b |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-81 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81 |
| filingDate |
2002-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83428e1972d637c7368ae2de134ec69e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecd0d4f164bbc48200c3a2a297a65ef6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2dd4a6fba04191c16aeff08342229f08 |
| publicationDate |
2003-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20030080933-A |
| titleOfInvention |
Production method of interleukin-18 using yeast expression system |
| abstract |
The present invention relates to a method for producing interleukin-18 protein using a yeast expression system, comprising: (a) a GPD promoter (glyceraldehyde-3-phosphate dehydrogenase; GenBank accession number M13807) or AG promoter (GenBank accession number J01314), (b) Provided are a vector comprising an extracellular secretion signal sequence, (c) a cytokine gene and (d) a transcription termination signal sequence, a transformant comprising the same, and a recombinant interleukin-18 protein. Recombinant interleukin-18 protein of the present invention can be used as an immuno-increasing composition for anti-viral and bacterial infections, as an anticancer composition as well as an antigen for the production of interleukin-18 antibody. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012057396-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100620495-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023128004-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101429536-B1 |
| priorityDate |
2002-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |