http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20030080782-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f63a69bd58c227c730629512a98e750d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec6e3fdbb98c39c66b28914a80f3de6a |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-20 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-163 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-44 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 |
filingDate | 2002-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a11f8fdac5e1e99479fa986bb837b66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e30fa174e4fc5fd103c6ebdefc393aec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_779ecd1e535e7b7bcc220774d30afb67 |
publicationDate | 2003-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20030080782-A |
titleOfInvention | The mass preparation method of monoclonal antibodies to methamphetamine |
abstract | The present invention relates to a mass production method of a single cell antibody against methamphetamine (MAP), which is a kind of drug.n n n Synthesis of methamphetamine with carrier proteins BSA and OA using DSS as coupling reagents, respectively, to prepare MAP-BSA conjugates used as immunogens and MAP-OA conjugates used for detection, and MAP-BSA conjugates prepared as immunogens. Was injected into mice and immunized. Splenocytes were harvested, fused with myeloma cells, and cultured in HAT medium to select a cell line producing monoclonal antibody against MAP using a detection MAP-OA conjugate. Next, it is composed of a method of injecting the antibody-producing cell line into the abdominal cavity of a mouse to obtain the ascites produced, purifying and obtaining a large amount of unicellular antibody against methamphetamine.n n n Mass-produced monocellular antibodies have high titers of antibodies, do not cross-react with transport proteins, and competitive inhibition occurs with increasing concentrations of methamphetamine, and does not cross-react with other proteins contained in urine, Used in diagnostic kits for amphetamine detection. |
priorityDate | 2002-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 134.