| abstract |
The present invention relates to methods of treating certain metabolic diseases, novel compounds, and their prodrugs, and / or pharmaceutically acceptable salts, pharmaceutical compositions comprising said compounds useful for the treatment of said diseases. In particular, the present invention relates to the use of novel compounds and compositions for the treatment of cardiovascular disease, diabetes, cancer, acidosis, and obesity, through the inhibition of malonyl-CoA decarboxylase (MCD). These compounds have the following general formulas:n n n n n n n n In the above formula, Y, C, R 1 , R 2 , R 6 , and R 7 are defined herein. |