http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20030076805-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fb65ab1b41c2067a40270436dc55a429 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-10 |
| filingDate | 2002-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_976c4b154e0b0ff251568870d092cfb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09b24e2564d68f90606b8dca9fa92177 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e8d02c996de35a17628964fc4159030 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c4d8d0363316e9f5f21b93f468299a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_802653c47f0d9672e3a1a412507d32b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e53df911eb2c46fe188bb6312b936b8a |
| publicationDate | 2003-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20030076805-A |
| titleOfInvention | Novel PNA Monomer Having Photo-labile Protecting Group |
| abstract | The present invention relates to a compound of formula (I) having a photo-labile protecting group as a monomer for preparing a peptide nucleic acid (PNA) oligomer and a method for preparing the same.n n n Formula (1)n n n In the above formula,n n n R isn n n Wherein R 1, R 2, R 3 and R 4 are the same or different and are each independently hydrogen, nitro group, nitrile group, halogen atom, (C 1 -C 4) alkyl group, (C 1 -C 4) alkoxy group, acyl group or An aryl group, or R 2 and R 3 form a five or six membered ring having two oxygen atoms; R 5 is H, a (C 1 -C 4) alkyl group or an aryl group; n is 0 or 1;n n n B is a nucleic acid base which is protected or unprotected and which exists either naturally or unnaturally. The present invention also relates to a method for producing a PNA oligomer from the novel monomers and a PNA chip which can be produced from the monomers.n n n Substituents having a sulfonyl group in the compound of formula (1) serve as a protecting group of the PNA backbone, activation of amide bond formation in PNA oligomer synthesis, and three roles applied to photolithography. The monomers of the present invention having these characteristics are PNA oligomers, PNA / DNA chimera, PNA / peptide conjugates and various labelable basic compounds using various combinatorial chemistry techniques. Can be used as In particular, the monomer of the present invention can be used to manufacture PNA chips that can replace DNA chips through exposure techniques. |
| priorityDate | 2002-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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