http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20030073553-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f0ad20eb72d0a4dc1cb5860ee6c332c1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-357 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-62 |
| filingDate | 2002-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_901f161720a6eaf5124a86c057f22942 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64610dae706b717ee313153113ee22c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9735fa158b868d08e4bad0f21385413 |
| publicationDate | 2003-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20030073553-A |
| titleOfInvention | Novel bioactive substance extracted from actinomycetes, method of extracting same, and pharmaceutical composition containing same |
| abstract | The present invention relates to a novel physiologically active substance extracted from cultured mycelium of Streptomyces genus Actinomycetes, the actinomycetes of Streptomyces genus are cultured in a liquid medium, the mycelium is isolated from the culture and extracted with an organic solvent, and then the solvent is evaporated. The residue is distributed according to polarity to obtain a polar organic concentrate, and the novel compound having the following structural formula obtained by separating and purifying the concentrate by chromatography is human leukemia, non-small cell lung cancer, uterine cancer, melanoma, large intestine. It is expected to be developed as a versatile anticancer agent by showing strong toxicity against cancer cells such as cancer and central nervous system cancer.n n n [Formula 1]n n n n n n n n Wherein R 1 and R 3 may be the same or different from each other and are each hydrogen, methyl or ethyl, and R 2 and R 4 may be the same or different from each other and are each hydrogen, methyl, ethyl, propyl or isopropyl, all asymmetric Isomers at carbon. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100768476-B1 |
| priorityDate | 2002-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.