| abstract |
The present invention relates to genetic variants of human beta, beta-carotene 15, 15'-deoxygenase with increased enzyme activity.n n n The genetic variant of the present invention is obtained by carrying out the error pron chain polymerase reaction method using the human beta, beta-carotene 15, 15'-deoxygenase gene as a template, and the enzymatic activity of the expressed protein is 1100 pmol / h /. It is characterized in that more than mg.n n n Therefore, the enzyme protein expressed from the genetic variants of the present invention can be usefully used in various fields related to the preparation of vitamin A. |