| abstract |
The present invention relates to methods and compositions for modifying peptides, polypeptides and proteins with polymers, in particular sugar-porous polymers, to improve their biological activity or pharmacokinetic properties. Moreover, the present invention provides methods and uses for such polymer-modified peptides, polypeptides and proteins. The present invention is particularly suitable for use in the synthesis of polymer-modified synthetic bioactive proteins and pharmaceutical compositions containing such proteins. |