http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20030055878-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33f8096f7c6f74ac787c777aaf01104a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-426 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0038 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-133 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-164 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-133 |
| filingDate | 2001-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e73292c6310b331931e5266060237dbd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dc3a4bc29f2735bcc4670a56c3c8e0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_421215da90090e83a919893529694130 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45325c8f3b6cb922a0b885993e0133ab |
| publicationDate | 2003-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20030055878-A |
| titleOfInvention | Radiosensitizer containing ceramides or derivatives thereof and dimethylsphingosine as the active ingredient |
| abstract | The present invention, ceramides and derivatives thereof and spingosine kinase inhibitor (sphingosine kinase inhibitor) The present invention relates to a radiation sensitizer comprising dimethylsphingosine together, and more particularly, to the present invention, the present invention provides a radiotherapy enhancing effect before or during irradiation of cancer cells to treat cancer in vivo. It relates to a novel radiation sensitivity enhancer comprising a ceramide compound of formula (1) and dimethylsphingosine of formula (4).n n n n n n n n n n (Wherein R 1 represents a substituted or unsubstituted alkyl group having 1 to 20 carbon atoms)n n n n n n n n n n Since the combination treatment of the compound improves the radiation treatment efficiency in cancer tissues, the same effect as the high dose treatment can be obtained while lowering the dose of radiation treatment in treating the ceramide and the radiation at a concentration that does not affect normal cells. In addition, since there is an effect that can significantly reduce the damage of normal cells, which is a side effect of high dose radiation treatment and high concentration ceramide administration, it is possible to maximize the efficiency of radiation therapy. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100459484-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100855355-B1 |
| priorityDate | 2001-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 116.