Predicate |
Object |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0082 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 |
filingDate |
2001-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2003-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20030053507-A |
titleOfInvention |
Lung surfactant compositions with dynamic swelling behaviour |
abstract |
The present invention relates to waste surfactant compositions capable of forming a dynamic expansion state upon dispersion in a medium comprising an electrolyte. The dynamic expansion process is observed by spectroscopic microscope and forms birefringence nets or tubules at the air / liquid interface. The dynamic expansion process causes the expansion of the lung surfactant with an increase in surface area compared to the expansion of the waste surfactant in the non-dynamic expansion state. Expansion occurs for a certain time after dispersion of the waste surfactant in the physiological electrolyte solution. Accordingly, the pulmonary surfactant may be more actively expanded into the alveoli after administration to the lung, and consequently the carrier for therapeutic, prophylactic and / or diagnostic active substances such compositions to the lung or other organs or inaccessible body parts. It leaves the possibility to use it as. The waste surfactant compositions of the present invention are air-containing within a time of about 0.5 to 120 minutes during expansion during observation by spectroscopic microscopy when dispersed as powders or particles in 0.9% w / w sodium chloride at a concentration of 10% w / w at room temperature. Lung surfactants capable of forming birefringence nets or tubules at the liquid-solid interface. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100891595-B1 |
priorityDate |
2000-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |