| abstract |
The present invention relates to the use of a strastol represented by the following formula (1), a serapanol represented by the formula (2), and a sesquiterpene ester compound represented by the formula (3) or a Novak dunk extract including the same, Compound and Novak Dungkul extract inhibits the phosphorylation of IκB and inhibits the degradation of IκB itself, thereby inhibiting the transcriptional activity of NF-κB and strongly inhibiting the production of iNOS, COX-2 and TNF, thereby treating inflammatory diseases and immunological diseases Or as a cancer therapeutic agent.n n n n n n n n n n n n n n n n n n n n n n n n (Wherein R 1 , R 2 , R 3 , and R 4 are as defined in the specification) |