abstract |
The present invention provides an aliphatic nitrogen-containing five-membered ring compound represented by the following formula (I) or a pharmacologically acceptable salt thereof.n n n <Formula I>n n n n n n n n In the formula,n n n A is -CH 2 -or -S-,n n n B is CH or N,n n n R 1 is H, a lower alkyl group, and the like,n n n X is a single bond, -CO-, -Alk-CO-, -COCH 2- , -Alk-O-, -O-CH 2- , -SO 2- , -S-, -COO-, -CON (R 3 )-, -Alk-CON (R 3 )-, -CON (R 3 ) CH 2- , -NHCH 2 -and the like, where R 3 is a hydrogen atom or a lower alkyl group and Alk is a lower alkylene group ,n n n R 2 is (1) a cyclic group which may be substituted, (2) a substituted amino group, or the like,n n n Provided that when X is -CO-, B is N. |