| abstract |
The present invention relates to a DNA encoding a polypeptide of the following (a), (b), (c) or (d).n n n (a) a polypeptide comprising the amino acid sequence represented by SEQ ID NO: 2 or 4,n n n (b) an amino acid sequence in which one or a plurality of amino acids are deleted, substituted, or added in the amino acid sequence represented by SEQ ID NO: 2 or 4, wherein hypophosphatemic induction activity, phosphate transport inhibitory activity, calcification inhibitory activity or in vivo vitamin D metabolism Polypeptides having regulatory activity,n n n (c) a polypeptide comprising a partial sequence of the amino acid sequence represented by SEQ ID NO: 2, wherein the partial sequence comprises at least the 34th to 201th amino acid sequences of the amino acid sequence, orn n n (d) a polypeptide comprising a partial sequence of an amino acid sequence represented by SEQ ID NO: 2, wherein the partial sequence comprises (i) at least the 34th to 201th amino acid sequences of the amino acid sequence, and (ii) the corresponding partial sequence A polypeptide comprising one or a plurality of amino acids in which the amino acid sequence is deleted, substituted or added, and (iii) has hypophosphatemic inducing activity, phosphoric acid transport inhibitory activity, calcification inhibitory activity or in vivo vitamin D metabolic regulatory activity. |