| abstract |
The present invention describes a novel tricyclic compound of Formula 1.0, a prodrug thereof, or a pharmaceutically acceptable salt or solvate of said compound or prodrug, useful for inhibiting farnesyl protein transferase:n n n Formula 1.0n n n n n n n n Also described herein are pharmaceutical compositions comprising the compounds, methods for their preparation, as well as methods of using them to treat proliferative diseases such as cancer. |