http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20030032443-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_580e310ec7051f2fb0a4c7257494c9a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_622fd00429475442776c4e23f514dfac http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4cc8d12fa1d3479453bc0e6fa588da5 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16052 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0693 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-867 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867 |
filingDate | 2001-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f8f34bd0c0df626e2419522034d18fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd87b2a81cbb043cc379aabb12b133cd |
publicationDate | 2003-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20030032443-A |
titleOfInvention | Tetracyclin inducible hiv-1 packaging cell line and a method for producing hiv-1 defective interfering particle using same |
abstract | The present invention relates to a tetracycline inducible packaging cell line, specifically a gene construct in which a portion of the packaging signal, Env, Nef and 3 'LTR in the HIV-1 genome is removed to act as a helper virus; A tetracycline reactive packaging construct comprising the gene construct; A packaging cell line transfected with the packaging construct to express a gene of interest only in the presence of tetracycline to package HIV-1 DI (defective interfering) particles; And to a method of producing HIV-1 DI particles using the same. The packaging cell line of the present invention can be usefully used for the production of HIV-1 DI particles by controlling the expression of accessory proteins essential for the induction of HIV-1 DI particles by using a tetracycline expression induction system to inhibit their cytotoxicity. have. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20030019282-A |
priorityDate | 2001-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 370.