http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20030027028-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N63-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N63-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N63-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-325 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
filingDate | 2001-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2003-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20030027028-A |
titleOfInvention | Improved insecticidal bacteria, and methods for making and using them |
abstract | The present invention relates to a BtI or BtII promoter, or a combination of BtI and BtII promoters, at least 6 contiguous nucleotides of the bacterial STAB-SD sequence and 41.9 kD protein of B. sphaericus (“Bs”) binary toxin. And a nucleic acid sequence comprising a sequence encoding a first polypeptide having at least 80% sequence identity and whose toxicity is at least 50% of the 41.9 kD toxin protein of SEQ ID NO: 9. Optionally, the sequence further encodes a second polypeptide having at least 80% sequence identity with the 51.4 kD protein of the Bs binary toxin and capable of functioning as a binding domain of the Bs 41.9 kD toxin protein. When nucleic acid sequences are expressed in B. thuringiensis (“Bt”) or Bs cells, they produce at least ten times the Bs binary protein of untransformed Bs cells. The present invention provides methods for increasing the toxicity of insecticidal bacteria by transforming the bacteria with nucleic acid sequences, expression vectors, host cells, and nucleic acid sequences of the present invention. Moreover, the present invention relates to the discovery that Cyt1Aa1 protein of Bt subspecies israelensis (“Bti”) reverses resistance to Bs binary toxins in larvae of Bs resistant mosquitoes. The present invention provides a Bs cell expressing the Bti Cyt1Aa1 protein, and a method for reducing resistance to Bs binary toxin by co-administration of the Cyt1Aa1 protein and Bs binary toxin. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010087628-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010087628-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101453437-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101416148-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101416150-B1 |
priorityDate | 2000-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 241.