| abstract |
The present invention provides bicyclic heterocycles of formula I, tautomers thereof, stereoisomers and salts thereof, in particular inorganic acids, organic acids, inorganic bases, which exhibit useful pharmacological properties, in particular an inhibitory effect on signal transduction mediated by tyrosine kinases. Or a physiologically acceptable salt thereof with an organic base. The invention also relates to the use of the bicyclic heterocycle for the treatment of diseases, in particular neoplastic and pulmonary and respiratory tract diseases, and to methods for their preparation.n n n Formula In n n n n n n n In Formula I above,n n n R a to R c are as defined in claims 1 to 7. |