| abstract |
The present invention relates to piperidine derivatives represented by the following formula (I) or nontoxic salts thereof. Since the compound represented by the formula (I) has PDE4 inhibitory activity, it is possible to prevent inflammatory diseases, diabetic diseases, allergic diseases, autoimmune diseases, osteoporosis, fractures, obesity, antidepression, Parkinson's disease, ischemia reperfusion disorders, leukemia, and / or the like. Or useful for treatment.n n n Formula In n n n n n n n In the above formula, symbols are as described in the specification. |