| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-351
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P- |
| filingDate |
2001-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2003-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20030013373-A |
| titleOfInvention |
Method of purifying a fermentation broth |
| abstract |
The present invention relates to a method for purifying statin compounds from fermentation broth by extraction and crystallization. The fermentation broth is subjected to a pretreatment procedure including alkali pretreatment and alkali purification. After the pretreatment procedure, the statin compound is extracted with hydrophobic solvent under acidic conditions and purified by crystallization. The organic extraction solvent is concentrated and then extracted with a weak base. The statin compound is then purified by crystallization. |
| priorityDate |
2000-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |