| abstract |
The present invention relates to compounds of formula (I), which advantageously inhibit or block the biological activity of picornavirus 3C proteases. Such compounds as well as pharmaceutical compositions comprising them are useful for treating a patient or host infected with one or more picornaviruses, eg, RVP. Also disclosed are intermediates and synthetic methods for preparing these compounds.n n n Formula In n n n n n n n Wheren n n Substituents are as defined above. |