| abstract |
An object of the present invention is to manufacture a substance having excellent delivery property that enables the drug to be effectively held for a long time in a living body, and to construct a drug delivery system using the delivery material. Administration of a polyalkylene glycol or its reactive derivatives, phospholipids and drugs to form a covalent bond resulting in systemic or topical administration results in long-term retention at the target site in vivo. It is possible to sustain the drug for a long time. |