abstract |
The present invention relates to dopamine and serotonin receptor ligands having the formula (I):n n n n n n n n Wherein one of Y 1 and Y 2 is N bonded to Y 4 , Y 3 is Z—CH 2 , CH 2 —Z, or CH 2 CH 2 , and Y 1 , Y 2 , Y 3 , Y 4 , Z, W, n, m, X, R 1 -R 9 , R 10 are as described in the specification and claims. The compounds of the present invention are useful for the treatment and improvement of sleep of certain psychotic and neurological disorders such as schizophrenia, other psychosis, anxiety disorders, depression, migraine, multiple cognitive dysfunction, ADHD. |