| abstract |
The present invention relates to a method for recombinant production of non-segmented negative-sense single stranded RNA virus, and immunogen compositions formed therefrom, via rescue of Mumps virus. Further aspects relate to methods of producing Mumps viruses as attenuated and / or infectious viruses. Recombinant viruses are prepared from cDNA clones, thus obtaining viruses with defined changes at the genomic site, including nucleotide / polynucleotide deletions, insertions, substitutions, and rearrangements. |