abstract |
It is an object of the present invention to provide antagonists of alpha-2 adrenoreceptors in which alpha-2 antagonists are useful in the treatment of diseases and conditions of the peripheral and central nervous system. Accordingly, it is an object of the present invention to provide compounds which are used as alpha-2 antagonists in the treatment of mammals, including humans and animals.n n n Another object of the present invention is to provide compounds useful as selective alpha-2C antagonists in the treatment of various diseases and conditions of the central nervous system where alpha-2C antagonists are useful. |