| abstract |
The present invention relates to mammalian species in need of treating a synergistically effective amount of one or more agents selected from the group consisting of cytotoxic agents and growth inhibitors, and (2) compounds of formula (I) or pharmaceutically acceptable salts thereof. It provides a method for treating cancer having a synergistic effect comprising administering to. The invention also provides a synergistic cancer therapeutic pharmaceutical composition comprising an anti-proliferative cytotoxic agent and an anti-proliferative growth inhibitor, at least one agent selected from the group consisting of compounds of formula (I) and a pharmaceutically acceptable carrier. To provide.n n n <Formula I> |