abstract |
The present invention relates to the use of a flavonol derivative having a structure of Formula 1 in the prevention or treatment of hepatitis B. Flavonol derivatives comprising myricetin having a structure of Formula 2, quercetin having a structure of Formula 3, morin having a structure of Formula 4, or a pharmaceutically acceptable salt thereof Suppresses the production of hepatitis B virus e antigen, which keeps viral hepatitis in a chronic state, and can be usefully used as a therapeutic agent for chronic and acute hepatitis because of low cytotoxicity.n n n <Formula 1>n n n n n n n n In Formula 1, R 1 , R 2 , R 3 and R 4 are independent of each other, and are H, OH or an alkoxy group of C 1 to C 3 .n n n <Formula 2>n n n n n n n n <Formula 3>n n n n n n n n <Formula 4> |