http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20020079731-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4711 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0207 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate | 2000-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2002-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20020079731-A |
titleOfInvention | Peptide Analogs and Mimetics Suitable for in Vivo Use in the Treatment of Diseases Associated with Abnormal Protein Folding into Amyloid, Amyloid-like Deposits or β-Sheet Rich Pathological Precursor Thereof |
abstract | The present invention is an inhibitory peptide capable of inhibiting β-wrinkle sheet formation in amyloid β-peptide. The inhibitory peptides are β-sheet breaker peptide homologs designed by chemically modifying β-sheet breaker peptides capable of inhibiting β-wrinkled sheet formation in amyloid β-peptides. The present invention also includes inhibitory peptides capable of inhibiting conformational changes of prion PrP proteins associated with amyloidosis. The inhibitory peptide is a β-sheet breaker peptide homolog designed by chemically modifying the β-sheet breaker peptide capable of inhibiting the conformational change of prion PrP protein associated with amyloidosis. The present invention also encompasses peptide analogs having a PMiAβ5 structure. In another embodiment, the peptide analog has a PMiPrP13 structure. In another embodiment, the peptide analog has a PMiPrP5 structure of the formula |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20150111628-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9822149-B2 |
priorityDate | 1999-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 337.